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The Drosophila Insulin Receptor Independently Modulates Lifespan and Locomotor Senescence

The Insulin/IGF-like signalling (IIS) pathway plays an evolutionarily conserved role in ageing. In model organisms reduced IIS extends lifespan and ameliorates some forms of functional senescence. However, little is known about IIS in nervous system ageing and behavioural senescence. To investigate...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Ismail, Mohd Zamri Bin Haji, Hodges, Matt D., Boylan, Michael, Achall, Rajesh, Shirras, Alan, Broughton, Susan J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447345/
https://ncbi.nlm.nih.gov/pubmed/26020640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125312
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