Drosophila germ-line modulation of insulin signaling and lifespan

Ablation of germ-line precursor cells in Caenorhabditis elegans extends lifespan by activating DAF-16, a forkhead transcription factor (FOXO) repressed by insulin/insulin-like growth factor (IGF) signaling (IIS). Signals from the gonad might thus regulate whole-organism aging by modulating IIS. To d...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Flatt, Thomas, Min, Kyung-Jin, D'Alterio, Cecilia, Villa-Cuesta, Eugenia, Cumbers, John, Lehmann, Ruth, Jones, D. Leanne, Tatar, Marc
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2008
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359818/
https://ncbi.nlm.nih.gov/pubmed/18434551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709128105
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍