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HAMP Domain Rotation and Tilting Movements Associated with Signal Transduction in the PhoQ Sensor Kinase

HAMP domains are α-helical coiled coils that often transduce signals from extracytoplasmic sensing domains to cytoplasmic domains. Limited structural information has resulted in hypotheses that specific HAMP helix movement changes downstream enzymatic activity. These hypotheses were tested by mutage...

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Publicat a:mBio
Autors principals: Matamouros, Susana, Hager, Kyle R., Miller, Samuel I.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447245/
https://ncbi.nlm.nih.gov/pubmed/26015499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00616-15
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