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Assembly of the Transmembrane Domain of E. coli PhoQ Histidine Kinase: Implications for Signal Transduction from Molecular Simulations

The PhoQP two-component system is a signaling complex essential for bacterial virulence and cationic antimicrobial peptide resistance. PhoQ is the histidine kinase chemoreceptor of this tandem machine and assembles in a homodimer conformation spanning the bacterial inner membrane. Currently, a full...

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Autors principals: Lemmin, Thomas, Soto, Cinque S., Clinthorne, Graham, DeGrado, William F., Dal Peraro, Matteo
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554529/
https://ncbi.nlm.nih.gov/pubmed/23359663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002878
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