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Mesenchyme-specific overexpression of nucleolar protein 66 in mice inhibits skeletal growth and bone formation

Previous studies showed that nucleolar protein 66 (NO66), the Jumonji C-domain-containing histone demethylase for methylated histone H3K4 and H3K36 (H3K36me), negatively regulates osteoblast differentiation in vitro by inhibiting the activity of transcription factor osterix (Osx). However, whether N...

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書目詳細資料
發表在:FASEB J
Main Authors: Chen, Qin, Zhang, Liping, de Crombrugghe, Benoit, Krahe, Ralf
格式: Artigo
語言:Inglês
出版: Federation of American Societies for Experimental Biology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447221/
https://ncbi.nlm.nih.gov/pubmed/25746793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-258970
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