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Overexpression of Bone Sialoprotein Leads to an Uncoupling of Bone Formation and Bone Resorption in Mice

The purpose of this study was to determine the effects of bone sialoprotein (BSP) overexpression in bone metabolism in vivo by using a homozygous transgenic mouse line that constitutively overexpresses mouse BSP cDNA driven by the cytomegalovirus (CMV) promoter. CMV-BSP transgenic (TG) mice and wild...

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Detalhes bibliográficos
Main Authors: Valverde, Paloma, Zhang, Jin, Fix, Amanda, Zhu, Ji, Ma, Wenli, Tu, Qisheng, Chen, Jake
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685486/
https://ncbi.nlm.nih.gov/pubmed/18597627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080605
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