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Overexpression of Bone Sialoprotein Leads to an Uncoupling of Bone Formation and Bone Resorption in Mice

The purpose of this study was to determine the effects of bone sialoprotein (BSP) overexpression in bone metabolism in vivo by using a homozygous transgenic mouse line that constitutively overexpresses mouse BSP cDNA driven by the cytomegalovirus (CMV) promoter. CMV-BSP transgenic (TG) mice and wild...

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Autores principales: Valverde, Paloma, Zhang, Jin, Fix, Amanda, Zhu, Ji, Ma, Wenli, Tu, Qisheng, Chen, Jake
Formato: Artigo
Lenguaje:Inglês
Publicado: Amer Soc Bone & Mineral Res. 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685486/
https://ncbi.nlm.nih.gov/pubmed/18597627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080605
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