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Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation

Our previous studies indicated that the Jumonji C (JmjC)-domain-containing NO66 is a histone demethylase with specificity for methylated histone H3K4 and H3K36. NO66 binds to the transcription factor Osterix (Osx) and inhibits its transcriptional activity in promoter assays. However, the physiologic...

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Bibliografiske detaljer
Udgivet i:J Bone Miner Res
Main Authors: Chen, Qin, Sinha, Krishna, Deng, Jian Min, Yasuda, Hideyo, Krahe, Ralf, Behringer, Richard R., de Crombrugghe, Benoit
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780322/
https://ncbi.nlm.nih.gov/pubmed/25736226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2494
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