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Amyloid-β-induced amyloid-β secretion: A possible feed-forward mechanism in Alzheimer disease

Amyloid beta (Aβ) peptides, 36-43 amino acids in length, are produced from β- and γ-secretase cleavage of the amyloid precursor protein (AβPP), and are one of the causative agents of Alzheimer disease (AD). Here we show that an ELISA can detect total rodent Aβ without interference from physiological...

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Bibliografische gegevens
Gepubliceerd in:J Alzheimers Dis
Hoofdauteurs: Marsden, Ian T., Minamide, Laurie S., Bamburg, James R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447202/
https://ncbi.nlm.nih.gov/pubmed/21297255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-101899
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