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Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation
BACKGROUND: Previously we reported 1 μM synthetic human amyloid beta(1-42 )oligomers induced cofilin dephosphorylation (activation) and formation of cofilin-actin rods within rat hippocampal neurons primarily localized to the dentate gyrus. RESULTS: Here we demonstrate that a gel filtration fraction...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037337/ https://ncbi.nlm.nih.gov/pubmed/21261978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-6-10 |
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