Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells

A method for stimulating the differentiation of human pluripotent stem cells (hPSCs) into kidney lineages remains to be developed. Most cells in kidney are derived from an embryonic germ layer known as intermediate mesoderm (IM). Here we show the establishment of an efficient system of homologous re...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Mae, Shin-Ichi, Shono, Akemi, Shiota, Fumihiko, Yasuno, Tetsuhiko, Kajiwara, Masatoshi, Gotoda-Nishimura, Nanaka, Arai, Sayaka, Sato-Otubo, Aiko, Toyoda, Taro, Takahashi, Kazutoshi, Nakayama, Naoki, Cowan, Chad A., Aoi, Takashi, Ogawa, Seishi, McMahon, Andrew P., Yamanaka, Shinya, Osafune, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4447148/
https://ncbi.nlm.nih.gov/pubmed/23340407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2378
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