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Efficient and Rapid Induction of Human iPSCs/ESCs into Nephrogenic Intermediate Mesoderm Using Small Molecule-Based Differentiation Methods

The first step in developing regenerative medicine approaches to treat renal diseases using pluripotent stem cells must be the generation of intermediate mesoderm (IM), an embryonic germ layer that gives rise to kidneys. In order to achieve this goal, establishing an efficient, stable and low-cost m...

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Bibliografische gegevens
Hoofdauteurs: Araoka, Toshikazu, Mae, Shin-ichi, Kurose, Yuko, Uesugi, Motonari, Ohta, Akira, Yamanaka, Shinya, Osafune, Kenji
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893162/
https://ncbi.nlm.nih.gov/pubmed/24454758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084881
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