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On the mechanism of RNA phosphodiester backbone cleavage in the absence of solvent

Ribonucleic acid (RNA) modifications play an important role in the regulation of gene expression and the development of RNA-based therapeutics, but their identification, localization and relative quantitation by conventional biochemical methods can be quite challenging. As a promising alternative, m...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Autores principales: Riml, Christian, Glasner, Heidelinde, Rodgers, M. T., Micura, Ronald, Breuker, Kathrin
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446422/
https://ncbi.nlm.nih.gov/pubmed/25904631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv288
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