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Native Contact Density and Nonnative Hydrophobic Effects in the Folding of Bacterial Immunity Proteins

The bacterial colicin-immunity proteins Im7 and Im9 fold by different mechanisms. Experimentally, at pH 7.0 and 10°C, Im7 folds in a three-state manner via an intermediate but Im9 folding is two-state-like. Accordingly, Im7 exhibits a chevron rollover, whereas the chevron arm for Im9 folding is line...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Chen, Tao, Chan, Hue Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446218/
https://ncbi.nlm.nih.gov/pubmed/26016652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004260
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