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Resveratrol Attenuates Microvascular Inflammation in Sepsis via SIRT-1-induced Modulation of adhesion molecules in ob/ob mice
OBJECTIVE: Obesity, a Sirtuin-1 (SIRT-1) deficient state, increases morbidity and resource utilization in critically ill patients. SIRT-1 deficiency increases microvascular inflammation and mortality in early sepsis. Our objective was to study the effect of resveratrol (RSV), a SIRT-1 activator, on...
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| Published in: | Obesity (Silver Spring) |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4446191/ https://ncbi.nlm.nih.gov/pubmed/25959124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.21086 |
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