Fluorescence Linked Enzyme Chemoproteomic Strategy for Discovery of a Potent and Selective DAPK1 and ZIPK Inhibitor

[Image: see text] DAPK1 and ZIPK (also called DAPK3) are closely related serine/threonine protein kinases that regulate programmed cell death and phosphorylation of non-muscle and smooth muscle myosin. We have developed a fluorescence linked enzyme chemoproteomic strategy (FLECS) for the rapid ident...

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Argitaratua izan da:ACS Chem Biol
Egile Nagusiak: Carlson, David A., Franke, Aaron S., Weitzel, Douglas H., Speer, Brittany L., Hughes, Philip F., Hagerty, Laura, Fortner, Christopher N., Veal, James M., Barta, Thomas E., Zieba, Bartosz J., Somlyo, Avril V., Sutherland, Cindy, Deng, Jing Ti, Walsh, Michael P., MacDonald, Justin A., Haystead, Timothy A. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445880/
https://ncbi.nlm.nih.gov/pubmed/24070067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb400407c
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