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Engineering the Substrate Specificity of ADP-Ribosyltransferases for Identifying Direct Protein Targets
Adenosine diphosphate ribosyltransferases (ARTDs; ARTD1–17 in humans) are emerging as critical regulators of cell function in both normal physiology and disease. These enzymes transfer the ADP-ribose moiety from its substrate, nicotinamide adenine dinucleotide (NAD(+)), to amino acids of target prot...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445677/ https://ncbi.nlm.nih.gov/pubmed/24641686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja412897a |
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