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Ribosome mediated specificity in Hox mRNA translation and vertebrate tissue patterning

Historically, the ribosome has been viewed as a complex ribozyme with constitutive rather than regulatory capacity in mRNA translation. Here we identify mutations of the Ribosomal Protein L38 (Rpl38) gene in mice exhibiting surprising tissue specific patterning defects, including pronounced homeotic...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Kondrashov, Nadya, Pusic, Aya, Stumpf, Craig R., Shimizu, Kunihiko, Hsieh, Andrew C., Ishijima, Junko, Shiroishi, Toshihiko, Barna, Maria
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445650/
https://ncbi.nlm.nih.gov/pubmed/21529712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.028
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