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Ribosome mediated specificity in Hox mRNA translation and vertebrate tissue patterning

Historically, the ribosome has been viewed as a complex ribozyme with constitutive rather than regulatory capacity in mRNA translation. Here we identify mutations of the Ribosomal Protein L38 (Rpl38) gene in mice exhibiting surprising tissue specific patterning defects, including pronounced homeotic...

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發表在:Cell
Main Authors: Kondrashov, Nadya, Pusic, Aya, Stumpf, Craig R., Shimizu, Kunihiko, Hsieh, Andrew C., Ishijima, Junko, Shiroishi, Toshihiko, Barna, Maria
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445650/
https://ncbi.nlm.nih.gov/pubmed/21529712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.028
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