Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio

Insulinomas cause neuroglycopenic symptoms, permanent neurological damage and even death. Current available therapies cannot satisfactorily treat malignant insulinomas and some benign insulinomas. The promising phototherapeutic results and harmless side effects of hypericin in some cancer treatments...

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Dades bibliogràfiques
Publicat a:Biosci Rep
Autors principals: Yi, Jingwen, Yang, Xiaoguang, Zheng, Lihua, Yang, Guang, Sun, Luguo, Bao, Yongli, Wu, Yin, Huang, Yanxin, Yu, Chunlei, Yang, Shao-Nian, Li, Yuxin
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2015
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445353/
https://ncbi.nlm.nih.gov/pubmed/26182357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150028
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