Photoactivation of hypericin decreases the viability of RINm5F insulinoma cells through reduction in JNK/ERK phosphorylation and elevation of caspase-9/caspase-3 cleavage and Bax-to-Bcl-2 ratio

Insulinomas cause neuroglycopenic symptoms, permanent neurological damage and even death. Current available therapies cannot satisfactorily treat malignant insulinomas and some benign insulinomas. The promising phototherapeutic results and harmless side effects of hypericin in some cancer treatments...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Biosci Rep
Asıl Yazarlar: Yi, Jingwen, Yang, Xiaoguang, Zheng, Lihua, Yang, Guang, Sun, Luguo, Bao, Yongli, Wu, Yin, Huang, Yanxin, Yu, Chunlei, Yang, Shao-Nian, Li, Yuxin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2015
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445353/
https://ncbi.nlm.nih.gov/pubmed/26182357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150028
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