Depletion of Amyloid Precursor Protein (APP) causes G0 arrest in non-small cell lung cancer (NSCLC) cells

We recently reported that Amyloid Precursor Protein (APP) regulates global protein synthesis in a variety of human dividing cells, including non-small cell lung cancer (NSCLC) cells. More specifically, APP depletion causes an increase of both cap- and IRES-dependent translation. Since growth and pro...

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Vydáno v:J Cell Physiol
Hlavní autoři: Sobol, Anna, Galluzzo, Paola, Weber, Megan J., Alani, Sara, Bocchetta, Maurizio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445075/
https://ncbi.nlm.nih.gov/pubmed/25502341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24875
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