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Amyloid Precursor Protein (APP) Affects Global Protein Synthesis in Dividing Human Cells
Hypoxic non‐small cell lung cancer (NSCLC) is dependent on Notch‐1 signaling for survival. Targeting Notch‐1 by means of γ‐secretase inhibitors (GSI) proved effective in killing hypoxic NSCLC. Post‐mortem analysis of GSI‐treated, NSCLC‐burdened mice suggested enhanced phosphorylation of 4E‐BP1 at th...
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| Pubblicato in: | J Cell Physiol |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445069/ https://ncbi.nlm.nih.gov/pubmed/25283437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24835 |
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