Caricamento...

Amyloid Precursor Protein (APP) Affects Global Protein Synthesis in Dividing Human Cells

Hypoxic non‐small cell lung cancer (NSCLC) is dependent on Notch‐1 signaling for survival. Targeting Notch‐1 by means of γ‐secretase inhibitors (GSI) proved effective in killing hypoxic NSCLC. Post‐mortem analysis of GSI‐treated, NSCLC‐burdened mice suggested enhanced phosphorylation of 4E‐BP1 at th...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Cell Physiol
Autori principali: Sobol, Anna, Galluzzo, Paola, Liang, Shuang, Rambo, Brittany, Skucha, Sylvia, Weber, Megan J., Alani, Sara, Bocchetta, Maurizio
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445069/
https://ncbi.nlm.nih.gov/pubmed/25283437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24835
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !