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A comparison of AAV strategies distinguishes overlapping vectors for efficient systemic delivery of the 6.2 kb Dysferlin coding sequence
Recombinant adeno-associated virus (rAAV) is currently the best vector for gene delivery into the skeletal muscle. However, the 5-kb packaging size of this virus is a major obstacle for large gene transfer. This past decade, many different strategies were developed to circumvent this issue (concatem...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Ther Methods Clin Dev |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Nature Publishing Group
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4445010/ https://ncbi.nlm.nih.gov/pubmed/26029720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.9 |
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