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Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors

Viral vectors derived from adeno-associated viruses (AAV) are widely used for gene transfer both in vitro and in vivo. The increasing use of AAV as a gene transfer vector, as well as recently demonstrated immunological complications in clinical trials, highlight the necessity to define the specific...

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Detalhes bibliográficos
Main Authors: Zeltner, Nadja, Kohlbrenner, Erik, Clément, Nathalie, Weber, Thomas, Linden, R. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900506/
https://ncbi.nlm.nih.gov/pubmed/20336156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2010.27
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