Antiviral Activity of TMC353121, a Respiratory Syncytial Virus (RSV) Fusion Inhibitor, in a Non-Human Primate Model

BACKGROUND: The study assessed the antiviral activity of TMC353121, a respiratory syncytial virus (RSV) fusion inhibitor, in a preclinical non-human primate challenge model with a viral shedding pattern similar to that seen in humans, following continuous infusion (CI). METHODS: African green monkey...

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Vydáno v:PLoS One
Hlavní autoři: Ispas, Gabriela, Koul, Anil, Verbeeck, Johan, Sheehan, Jennifer, Sanders-Beer, Brigitte, Roymans, Dirk, Andries, Koen, Rouan, Marie-Claude, De Jonghe, Sandra, Bonfanti, Jean-François, Vanstockem, Marc, Simmen, Kenneth, Verloes, Rene
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444337/
https://ncbi.nlm.nih.gov/pubmed/26010881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126959
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