Solenopsin A and analogs exhibit ceramide-like biological activity

BACKGROUND: (−)-Solenopsin A is a piperidine alkaloid that is a component of the venom of the fire ant Solenopsis invicta. Previously, we have demonstrated that solenopsin exhibit anti-angiogenic activity and downregulate phosphoinositol-3 kinase (PI3K) in the p53 deficient renal cell carcinoma cell...

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Publicado en:Vasc Cell
Autores principales: Karlsson, Isabella, Zhou, Xin, Thomas, Raquela, Smith, Allorie T, Bonner, Michael Y, Bakshi, Pooja, Banga, Ajay K, Bowen, J Phillip, Qabaja, Ghassan, Ford, Shavon L, Ballard, Matthew D, Petersen, Kimberly S, Li, Xuechen, Chen, Guangping, Ogretmen, Besim, Zhang, Jin, Watkins, E Blake, Arnold, Rebecca S, Arbiser, Jack L
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443652/
https://ncbi.nlm.nih.gov/pubmed/26015865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13221-015-0030-2
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