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p53 induction is associated with neuronal damage in the central nervous system.

The p53 tumor-suppressor gene encodes a growth-regulatory protein that has been implicated in programmed cell death. To investigate the possible role of p53 in neuronal death, we studied p53 expression associated with excitotoxicity in the adult rat brain. Within hours of systemic administration of...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Sakhi, S, Bruce, A, Sun, N, Tocco, G, Baudry, M, Schreiber, S S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44434/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7525
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