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G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity

Kv7.4 channels are a crucial determinant of arterial diameter both at rest and in response to endogenous vasodilators. However, nothing is known about the factors that ensure effective activity of these channels. We report that G-protein βγ subunits increase the amplitude and activation rate of whol...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Stott, Jennifer B., Povstyan, Oleksandr V., Carr, Georgina, Barrese, Vincenzo, Greenwood, Iain A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443360/
https://ncbi.nlm.nih.gov/pubmed/25941381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418605112
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