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G-protein βγ subunits are positive regulators of Kv7.4 and native vascular Kv7 channel activity
Kv7.4 channels are a crucial determinant of arterial diameter both at rest and in response to endogenous vasodilators. However, nothing is known about the factors that ensure effective activity of these channels. We report that G-protein βγ subunits increase the amplitude and activation rate of whol...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4443360/ https://ncbi.nlm.nih.gov/pubmed/25941381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418605112 |
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