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Synergistic interplay of Gβγ and phosphatidylinositol 4,5-bisphosphate dictates Kv7.4 channel activity
Kv7.4 channels are key determinants of arterial contractility and cochlear mechanosensation that, like all Kv7 channels, have an obligatory requirement for phosphatidylinositol 4,5-bisphosphate (PIP(2)). βγ G proteins (Gβγ) have been identified as novel positive regulators of Kv7.4. The present stud...
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| Published in: | Pflugers Arch |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Berlin Heidelberg
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5222924/ https://ncbi.nlm.nih.gov/pubmed/27981364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1916-4 |
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