Apolipoprotein A-I mimetic peptide 4F blocks sphingomyelinase-induced LDL aggregation

Lipolytic modification of LDL particles by SMase generates LDL aggregates with a strong affinity for human arterial proteoglycans and may so enhance LDL retention in the arterial wall. Here, we evaluated the effects of apoA-I mimetic peptide 4F on structural and functional properties of the SMase-mo...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Nguyen, Su Duy, Javanainen, Matti, Rissanen, Sami, Zhao, Hongxia, Huusko, Jenni, Kivelä, Annukka M., Ylä-Herttuala, Seppo, Navab, Mohamad, Fogelman, Alan M., Vattulainen, Ilpo, Kovanen, Petri T., Öörni, Katariina
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442877/
https://ncbi.nlm.nih.gov/pubmed/25861792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M059485
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