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Proteolysis sensitizes LDL particles to phospholipolysis by secretory phospholipase A(2) group V and secretory sphingomyelinase
LDL particles that enter the arterial intima become exposed to proteolytic and lipolytic modifications. The extracellular hydrolases potentially involved in LDL modification include proteolytic enzymes, such as chymase, cathepsin S, and plasmin, and phospholipolytic enzymes, such as secretory phosph...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2882729/ https://ncbi.nlm.nih.gov/pubmed/20124257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M003103 |
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