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Detection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans.

Exocyclic adducts are unique DNA modifications resulting from binding at two sites of bases that normally are involved in hydrogen-bonding for maintaining the double-helical structure of DNA. These adducts have been shown to be formed in rodents upon exposure to carcinogens. Using a sensitive 32P-po...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Nath, R G, Chung, F L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052609/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7491
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