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Detection of exocyclic 1,N2-propanodeoxyguanosine adducts as common DNA lesions in rodents and humans.
Exocyclic adducts are unique DNA modifications resulting from binding at two sites of bases that normally are involved in hydrogen-bonding for maintaining the double-helical structure of DNA. These adducts have been shown to be formed in rodents upon exposure to carcinogens. Using a sensitive 32P-po...
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Main Authors: | , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
1994
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC44427/ https://ncbi.nlm.nih.gov/pubmed/8052609 |
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