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Analysis of Acrolein-Derived 1, N(2)-Propanodeoxyguanosine Adducts in Human Leukocyte DNA from Smokers and Non-smokers

Cigarette smoking is a major source of human exposure to acrolein, a widespread environmental pollutant and toxicant that is also formed endogenously through metabolism of amino acids and polyamines, and lipid peroxidation. Acrolein reacts with DNA, producing two pairs of regioisomeric 1, N(2)-propa...

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Detalhes bibliográficos
Main Authors: Zhang, Siyi, Balbo, Silvia, Wang, Mingyao, Hecht, Stephen S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064499/
https://ncbi.nlm.nih.gov/pubmed/21090699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100321y
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