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Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde
The spectrum of mutations induced by the naturally occurring DNA adduct pyrimido[1,2-α]purin-10(3H)-one (M(1)G) was determined by site-specific approaches using M13 vectors replicated in Escherichia coli. M(1)G was placed at position 6256 in the (−)-strand of M13MB102 by ligating the oligodeoxynucle...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences of the USA
1997
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC23062/ https://ncbi.nlm.nih.gov/pubmed/9238032 |
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