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Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde

The spectrum of mutations induced by the naturally occurring DNA adduct pyrimido[1,2-α]purin-10(3H)-one (M(1)G) was determined by site-specific approaches using M13 vectors replicated in Escherichia coli. M(1)G was placed at position 6256 in the (−)-strand of M13MB102 by ligating the oligodeoxynucle...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Fink, Stephen P., Reddy, G. Ramachandra, Marnett, Lawrence J.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9238032/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.16.8652
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