Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde
The spectrum of mutations induced by the naturally occurring DNA adduct pyrimido[1,2-α]purin-10(3H)-one (M(1)G) was determined by site-specific approaches using M13 vectors replicated in Escherichia coli. M(1)G was placed at position 6256 in the (−)-strand of M13MB102 by ligating the oligodeoxynucle...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1997
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC23062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9238032/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.16.8652 |
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