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Alterations in Hemagglutinin Receptor-Binding Specificity Accompany the Emergence of Highly Pathogenic Avian Influenza Viruses

Highly pathogenic avian influenza viruses (HPAIVs) of hemagglutinin H5 and H7 subtypes emerge after introduction of low-pathogenic avian influenza viruses (LPAIVs) from wild birds into poultry flocks, followed by subsequent circulation and evolution. The acquisition of multiple basic amino acids at...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Heider, Alla, Mochalova, Larisa, Harder, Timm, Tuzikov, Alexander, Bovin, Nicolai, Wolff, Thorsten, Matrosovich, Mikhail, Schweiger, Brunhilde
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442535/
https://ncbi.nlm.nih.gov/pubmed/25741006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03304-14
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