Dengue Virus Evolution under a Host-Targeted Antiviral

The host-targeted antiviral drug UV-4B reduces viral replication and promotes survival in a mouse model of experimental dengue virus (DENV) infection. UV-4B is an iminosugar that inhibits the α-glucosidase family of enzymes and subsequently the folding of glycosylated proteins, both viral and host....

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Plummer, Emily, Buck, Michael D., Sanchez, Marisa, Greenbaum, Jason A., Turner, Julia, Grewal, Rajvir, Klose, Brennan, Sampath, Aruna, Warfield, Kelly L., Peters, Bjoern, Ramstedt, Urban, Shresta, Sujan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442503/
https://ncbi.nlm.nih.gov/pubmed/25762732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00028-15
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