Altered Expression Levels of MMP1, MMP9, MMP12, TIMP1, and IL-1β as a Risk Factor for the Elevated IOP and Optic Nerve Head Damage in the Primary Open-Angle Glaucoma Patients

The aim of presented work was to analyze the impact of particular polymorphic changes in the promoter regions of the -1607 1G/2G MMP1, -1562 C/T MMP9, -82 A/G MMP12, -511 C/T IL-1β, and 372 T/C TIMP1 genes on their expression level in POAG patients. Blood and aqueous humor samples acquired from 50 p...

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Markiewicz, Lukasz, Pytel, Dariusz, Mucha, Bartosz, Szymanek, Katarzyna, Szaflik, Jerzy, Szaflik, Jacek P., Majsterek, Ireneusz
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442285/
https://ncbi.nlm.nih.gov/pubmed/26120586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/812503
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