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ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes
Autophagy, an important catabolic pathway implicated in a broad spectrum of human diseases, begins by forming double membrane autophagosomes that engulf cytosolic cargo and ends by fusing autophagosomes with lysosomes for degradation(1,2). Membrane fusion activity is required for early biogenesis of...
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| Vydáno v: | Nature |
|---|---|
| Hlavní autoři: | , , , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4442024/ https://ncbi.nlm.nih.gov/pubmed/25686604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14147 |
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