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Pharmacokinetic and pharmacodynamic profile of bendamustine and its metabolites

PURPOSE: Bendamustine is a unique alkylating agent indicated for the treatment of chronic lymphocytic leukemia and rituximab-refractory, indolent B cell non-Hodgkin’s lymphoma. Despite the extensive experience with bendamustine, its pharmacokinetic profile has only recently been described. This over...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Darwish, Mona, Bond, Mary, Hellriegel, Edward, Robertson, Philmore, Chovan, James P.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441746/
https://ncbi.nlm.nih.gov/pubmed/25829094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-015-2727-6
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