Pharmacokinetics and Excretion of (14)C-Bendamustine in Patients with Relapsed or Refractory Malignancy

BACKGROUND: Bendamustine is an alkylating agent with clinical activity against a variety of hematologic malignancies and solid tumors. To assess the roles of renal and hepatic drug elimination pathways in the excretion and metabolism of bendamustine, a mass balance study was performed in patients wi...

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Библиографические подробности
Главные авторы: Dubbelman, Anne-Charlotte, Rosing, Hilde, Darwish, Mona, D’Andrea, Denise, Bond, Mary, Hellriegel, Edward, Robertson, Philmore, Beijnen, Jos H., Schellens, Jan H. M.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing AG 2013
Предметы:
Original Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627029/
https://ncbi.nlm.nih.gov/pubmed/23322528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40268-012-0001-5
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