Pharmacokinetic Profiles and Pharmacodynamic Effects for Methylone and Its Metabolites in Rats

3,4-Methylenedioxy-N-methylcathinone (methylone) is a new psychoactive substance and the β-keto analog of 3,4-methylenedioxy-N-methylamphetamine (MDMA). It is well established that MDMA metabolism produces bioactive metabolites. Here we tested the hypothesis that methylone metabolism in rats can for...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Elmore, Joshua S, Dillon-Carter, Ora, Partilla, John S, Ellefsen, Kayla N, Concheiro, Marta, Suzuki, Masaki, Rice, Kenner C, Huestis, Marilyn A, Baumann, Michael H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240186/
https://ncbi.nlm.nih.gov/pubmed/27658484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.213
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