Metabolic and molecular responses to leucine enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis

BACKGROUND: Skeletal muscle loss (sarcopenia) is a major clinical complication in alcoholic cirrhosis with no effective therapy. Skeletal muscle autophagic proteolysis and myostatin expression (inhibitor of protein synthesis) are increased in cirrhosis and believed to contribute to anabolic resistan...

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Detaylı Bibliyografya
Yayımlandı:Hepatology
Asıl Yazarlar: Tsien, Cynthia, Davuluri, Gangarao, Singh, Dharmvir, Allawy, Allawy, Ten Have, Gabriella AM, Thapaliya, Samjhana, Schulze, John M, Barnes, David, McCullough, Arthur J, Engelen, Marielle P.K.J., Deutz, Nicolaas E.P., Dasarathy, Srinivasan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441611/
https://ncbi.nlm.nih.gov/pubmed/25613922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27717
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