Metabolic and molecular responses to leucine enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis

BACKGROUND: Skeletal muscle loss (sarcopenia) is a major clinical complication in alcoholic cirrhosis with no effective therapy. Skeletal muscle autophagic proteolysis and myostatin expression (inhibitor of protein synthesis) are increased in cirrhosis and believed to contribute to anabolic resistan...

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Foilsithe in:Hepatology
Main Authors: Tsien, Cynthia, Davuluri, Gangarao, Singh, Dharmvir, Allawy, Allawy, Ten Have, Gabriella AM, Thapaliya, Samjhana, Schulze, John M, Barnes, David, McCullough, Arthur J, Engelen, Marielle P.K.J., Deutz, Nicolaas E.P., Dasarathy, Srinivasan
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441611/
https://ncbi.nlm.nih.gov/pubmed/25613922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27717
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