YAP1 REGULATES OCT4 ACTIVITY AND SOX2 EXPRESSION TO FACILITATE SELF-RENEWAL AND VASCULAR MIMICRY OF STEM-LIKE CELLS

Non-small cell lung cancer (NSCLC) is highly correlated with smoking and has very low survival rates. Multiple studies have shown that stem-like cells contribute to the genesis and progression of NSCLC. Our results show that the transcriptional co-activator YAP1, which is the oncogenic component of...

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Bibliografiska uppgifter
I publikationen:Stem Cells
Huvudupphovsmän: Bora-Singhal, Namrata, Nguyen, Jonathan, Schaal, Courtney, Perumal, Deepak, Singh, Sandeep, Coppola, Domenico, Chellappan, Srikumar
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441573/
https://ncbi.nlm.nih.gov/pubmed/25754111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1993
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