Liver Fibrosis Occurs Through Dysregulation of MyD88-dependent Innate B cell Activity

Chronic liver disease mediated by activation of hepatic stellate cells (HSCs) leads to liver fibrosis. Here, we postulated that the immune regulatory properties of HSCs might promote the profibrogenic activity of B cells. Fibrosis is completely attenuated in carbon tetrachloride (CCl(4))-treated B c...

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發表在:Hepatology
Main Authors: Thapa, Manoj, Chinnadurai, Raghavan, Velazquez, Victoria M., Tedesco, Dana, Elrod, Elizabeth, Han, Jin-Hwan, Sharma, Prachi, Ibegbu, Chris, Gewirtz, Andrew, Anania, Frank, Pulendran, Bali, Suthar, Mehul S., Grakoui, Arash
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441566/
https://ncbi.nlm.nih.gov/pubmed/25711908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27761
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