Liver Fibrosis Occurs Through Dysregulation of MyD88-dependent Innate B cell Activity

Chronic liver disease mediated by activation of hepatic stellate cells (HSCs) leads to liver fibrosis. Here, we postulated that the immune regulatory properties of HSCs might promote the profibrogenic activity of B cells. Fibrosis is completely attenuated in carbon tetrachloride (CCl(4))-treated B c...

詳細記述

保存先:
書誌詳細
出版年:Hepatology
主要な著者: Thapa, Manoj, Chinnadurai, Raghavan, Velazquez, Victoria M., Tedesco, Dana, Elrod, Elizabeth, Han, Jin-Hwan, Sharma, Prachi, Ibegbu, Chris, Gewirtz, Andrew, Anania, Frank, Pulendran, Bali, Suthar, Mehul S., Grakoui, Arash
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441566/
https://ncbi.nlm.nih.gov/pubmed/25711908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27761
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